WeAreTBI.org - The Social Support Network for People Living with Traumatic Brain Injury

Brain Injury Patient Medical Areas Neurology March 31, 2008 ExonHit released positive results from a phase I trial of EHT 0202 for the treatment of scopolamine-induced brain impairments. This randomized, double-blind, placebo-controlled, crossover study enrolled twelve young healthy subjects who received single administrations of EHT 0202 (40mg, 80mg, and 120mg) or placebo. The effects of EHT 0202 on scopolamine-induced cognitive impairments were assessed by using EEG recordings (spectral analysis and Event Related Potentials - ERPs) at the following time points: 1 hour 15 minutes, 2 hours 45 minutes, 4 hours 15 minutes and 5 hours 45 minutes post dose. The results of the spectral...

Traumatic Brain Injuries Patient Medical Areas Neurology Trauma/Emergency Medicine January 3, 2005 GlaxoSmithKline reported results from a study with Requip (ropinirole), an approved non-ergoline dopamine agonist being investigated for the treatment of Restless Legs Syndrome (RLS). The placebo-controlled study enrolled 267 subjects with moderate-to-severe primary RLS. Results demonstrated that that Requip Tablets effectively treated the symptoms of primary Restless Legs Syndrome (RLS) as assessed by improvements in symptoms, over 12 weeks. Improvements were significantly better for Requip than placebo on the IRLS Scale (-11.2 vs. -8.7; p = 0.0197). In addition, the drug showed significant improvements in sleep and quality of life in RLS patients...